Sie sind hier: Startseite Professuren Rohrbach, Alexander Forschung

Research overview

Information about our lab's research projects

Fast Super-resolution microscopy


We develop and improve fast super resolution imaging methods to investigate the high dynamics of living cells - with and without fluorescence

Project 1: Structured illumination microscopy (SIM)
>>> more information

Project 2: Rotating coherent scattering (ROCS) microscopy
>>> more information

Spiroplasm-Movie jpg 210frames 100pix.gif

Nano-mechanics of helical bacteria in optical line traps 

Spiroplasms are tiny and deformable bacteria without cell wall. Using scanning optical line traps and light scattering, we investigate their molecular driving concepts leading to fast switching between contraction and relaxation.

               >>> more information

Particle binding and uptake into cells

See a   >>> Graphical overview of the cell periphery interacting with particles

Project 1: Nano-mechanics of phagocytosis and filopodia
              >>> more information

Project 2: Cargo-transport of coupled molecular motors
              >>> more information

Project 3: Particle uptake in giant vesicles (GUV)
              >>> more information

Light-sheet microscopy with self-reconstructing beams

We shape the phase profile of iilluminating laser beams in fluorescence light-sheet microscopy (LSM) to optimize the propagation through biological material and thereby the 3D image quality.

Project 1:  Beam shaping with dynamic computer holograms 
              >>> more information

Project 2:  Bessel beam LSM with 2-photon excitation or STED     
             >>> more information

Momentum transport through bio-polymer networks

We investigate the frequency dependent viscoelastic properties of microtubules coupled by optically trapped beads as nucleation sites.

>>> more information

Cytoskelton dynamics  inside Bacteria

With fast super-resolution microscopy (TIRF-SIM) we investigate the dynamics of MreB filaments inside B.Subtilis. The protein cytoskeleton protein MreB is a key player for the syntheis of the bacterial cell wall.

>>> more information


Surface Imaging with optically trapped probes

Surface scanning with optically trapped probes in the presence of phase disturbing structures.

>>> more information

Plasmonic coupling of optically trapped particles

We use video rate spectroscopy and MHz interferometric particle tracking to to understand the formation of metal nanoparticles (NP) to more complex structures inside an optical trap.

>>> more information


Wave optics. We developed theories and program code to describe light propagation in inhomogeneous media, scattering, optical forces and advanced 3D imaging.  
>>> more information

Brownian Dynamics. We develop theories and program code to describe particular diffusion and binding in complex environments.      
>>> more information

Dynamic Particle interactions

Interferometric tracking of dynamic particle interactions with scanning line optical tweezers.

>>> more information




















Benutzerspezifische Werkzeuge